Management of spontaneous TLS, as with treatment-induced TLS, includes hydration, medication to reduce uric acid concentration, and correction of electrolyte abnormalities.
Aggressive repletion is the mainstay of therapy. B12 repletion leads to complete correction of hematologic abnormalities in at least two-thirds of patients.
The FDA has recommended that the company recall all unexpired drug products intended to be sterile and cease sterile operations until adequate corrections are made.
Since up to 30% ofstroke volume goes cephal-ad, a correction factor mustbe included in calculationsof stroke volume and car-diac output.
Like prerenal AKI, ATN can often be promptly corrected if treated aggressively and early with IV fluid resuscitation and correction of any precipitating factors.
Revisiting InpatientHyperglycemiaNew Recommendations,Evolving Data, and Practical Implications for ImplementationGuest Editor: Etie S. Moghissi, MD, FACE. A Supplement to ACP HospitalistRelease date: December 15, 2009Expiration date: December 31,