Search results for "Sepsis"
Sepsis guidelines review old questions, tackle new ones
The lead author of the Surviving Sepsis Campaign's latest guideline update highlighted the most important changes for hospitalists to know, including recommendations on the use of fluid and vasopressors.
https://acphospitalist.acponline.org/archives/2022/01/19/sepsis-experts-review-old-questions-tackle-new-ones.htm
19 Jan 2022
Vitamin C monotherapy did not reduce mortality in patients with septic shock
A double-blind, randomized controlled trial of 124 ICU patients with septic shock found that while 28-day mortality was lower in those who received IV vitamin C versus placebo, the absolute risk reduction did not reach statistical significance.
https://acphospitalist.acponline.org/archives/2022/01/12/vitamin-C-monotherapy-did-not-reduce-mortality-in-patients-with-septic-shock.htm
12 Jan 2022
ICU admission associated with worse outcomes in sepsis, better survival in acute respiratory failure
Patients admitted from the ED to the ICU with sepsis had worse survival and longer length of stay than those admitted to the wards, while patients with acute respiratory failure had better survival in the ICU than on a medical ward, a multicenter study found.
https://acphospitalist.acponline.org/weekly/archives/2021/12/08/3.htm
8 Dec 2021
Beta-lactam plus doxycycline associated with lower mortality in older patients with CAP
Compared to other guideline-concordant empiric therapies for patients with community-acquired pneumonia (CAP), beta-lactam plus doxycycline was associated with lower 30-day and 90-day mortality in a Veterans Affairs cohort study.
https://acphospitalist.acponline.org/weekly/archives/2021/11/17/2.htm
17 Nov 2021
Intravenous fluid management
A hypothetical case highlights the many reasons to provide IV fluid.
https://acphospitalist.acponline.org/archives/2021/11/expert-analysis-iv-fluids.htm
15 Nov 2021
Combating clots in COVID-19
Critical care experts advised on appropriate prophylaxis for ward and ICU patients as part of the CHEST 2021 conference.
https://acphospitalist.acponline.org/archives/2021/11/combating-clots-in-covid-19.htm
15 Nov 2021
Goal-concordant care frequently not provided for sepsis patients, even when documented
In a retrospective study, 60% of patients who had survived sepsis did not have goals of care assessed before hospital discharge, and among those who did, 32% did not receive goal-concordant care.
https://acphospitalist.acponline.org/weekly/archives/2021/10/27/3.htm
27 Oct 2021
Surviving Sepsis Campaign releases updated guidelines for hospitalized adults
Topics covered among the 93 recommendations include screening and early treatment of sepsis, hemodynamic management, ventilation, additional therapies, and long-term outcomes and goals of care. Changes include which sepsis risk scores are recommended.
https://acphospitalist.acponline.org/weekly/archives/2021/10/20/2.htm
20 Oct 2021
Heparin dosing for COVID-19 inpatients, expert perspectives on boosters
Two new trials offered some support for therapeutic anticoagulation in inpatients with elevated d-dimer levels. Antithrombotic therapy didn't prove helpful for outpatients with COVID-19. FDA advisors, an ACP/Annals forum, and recent research addressed vaccine effectiveness and boosters.
https://acphospitalist.acponline.org/weekly/archives/2021/10/20/1.htm
20 Oct 2021
High-dose vitamin C not associated with improved mortality in sepsis
A systematic review and meta-analysis found that while high-dose IV vitamin C was associated with less vasopressor use and better SOFA scores, it did not appear to be linked to significant improvement in short-term mortality rates.
https://acphospitalist.acponline.org/weekly/archives/2021/09/15/4.htm
15 Sep 2021