Search results for "Sepsis"
Cefepime-induced neurotoxicity
An elderly patient presented with confusion three days after a hospitalization for osteomyelitis.
https://acphospitalist.acponline.org/archives/2023/07/12/free/cefepime-induced-neurotoxicity.htm
12 Jul 2023
Study finds limited value to procalcitonin in identifying BSI on admission
Among patients with suspected bloodstream infections (BSIs) who had blood cultures and a procalcitonin test on admission, the sensitivity of procalcitonin at a cutoff of 0.5 ng/mL was 68%, and empiric antibiotic therapy use was not meaningfully different with positive or negative results.
https://acphospitalist.acponline.org/archives/2023/07/12/study-finds-limited-value-to-procalcitonin-in-identifying-bsi-on-admission.htm
12 Jul 2023
Procalcitonin do's and don'ts
Although the optimal use of procalcitonin is still up for debate, there are best practices for getting the most bang for this blood test.
https://acphospitalist.acponline.org/archives/2023/07/05/free/procalcitonin-dos-and-donts.htm
5 Jul 2023
At a year, after-effects of COVID-19 hospitalization other than VTE similar to flu, sepsis
Compared to patients hospitalized with flu or sepsis, those with COVID-19 had increased risk of venous thromboembolism (VTE), stroke, depression, and anxiety in the 30 days after discharge, but over a year, only the risk for VTE was significantly elevated.
https://acphospitalist.acponline.org/archives/2023/06/28/free/at-a-year-after-effects-of-covid-19-hospitalization-other-than-vte-similar-to-flu-sepsis.htm
28 Jun 2023
Myocardial infarction
Be sure to distinguish between type 1 and type 2 when documenting care for a patient with acute myocardial infarction.
https://acphospitalist.acponline.org/archives/2023/06/28/myocardial-infarction.htm
28 Jun 2023
Continuous vs. intermittent meropenem administration did not improve outcomes in sepsis
A composite outcome of mortality and new antimicrobial resistance did not differ by whether critically ill patients received an equal dose of the beta-lactam antibiotic continuously or intermittently, an international randomized trial found.
https://acphospitalist.acponline.org/archives/2023/06/21/continuous-vs-intermittent-meropenem-administration-did-not-improve-outcomes-in-sepsis.htm
21 Jun 2023
Review finds no significant difference between IV fluid strategies in sepsis
A systematic review and meta-analysis of 13 trials found that all-cause mortality and rates of serious adverse events did not seem to vary by whether sepsis patients received lower or higher fluid volumes.
https://acphospitalist.acponline.org/archives/2023/05/10/review-finds-no-significant-difference-between-iv-fluid-strategies-in-sepsis.htm
10 May 2023
Sepsis scores perform poorly in COVID-19 patients, study finds
In the latest COVID-19 news, a retrospective analysis tested common inpatient risk scores using data from patients who presented to EDs early in the pandemic, and the FDA authorized additional boosters for older and immunocompromised patients.
https://acphospitalist.acponline.org/archives/2023/04/26/free/sepsis-scores-perform-poorly-in-covid-19-patients-study-finds.htm
26 Apr 2023
Antibiotic regimens differ in associated risk of AKI in critically ill patients
Vancomycin and piperacillin/tazobactam were associated with a higher risk of acute kidney injury (AKI) than either vancomycin and cefepime or vancomycin and meropenem in ICU patients, particularly at longer durations and in those with normal kidney function on admission.
https://acphospitalist.acponline.org/archives/2023/04/19/antibiotic-regimens-differ-in-associated-risk-of-aki-in-critically-ill-patients.htm
19 Apr 2023
Septic shock outcomes better in patients who got hydrocortisone plus fludrocortisone
A retrospective analysis of patients hospitalized with septic shock and receiving norepinephrine found that 47.2% of those who began hydrocortisone and fludrocortisone simultaneously died in the hospital or were discharged to hospice, compared to 50.8% of those treated with hydrocortisone alone.
https://acphospitalist.acponline.org/archives/2023/04/05/septic-shock-outcomes-better-in-patients-who-got-hydrocortisone-plus-fludrocortisone.htm
5 Apr 2023