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Ventilation helmets didn't reduce need for respiratory support in COVID-19 patients

ICU patients with COVID-19 respiratory failure who were randomized to ventilation by helmet did have a lower rate of endotracheal intubation than those given high-flow oxygen, an Italian trial found.
https://acphospitalist.acponline.org/weekly/archives/2021/03/31/2.htm
31 Mar 2021

Support protocol for ICU patients after extubation didn't reduce reintubation rates

The trial compared a respiratory therapist-driven protocol that provided noninvasive ventilation or high-flow nasal cannula to patients after extubation to usual care and found no significant differences.
https://acphospitalist.acponline.org/weekly/archives/2021/04/14/4.htm
14 Apr 2021

Late diagnoses, routine cultures, and more

Research summaries from ACP Hospitalist Weekly.
https://acphospitalist.acponline.org/archives/2021/05/recent-research.htm
15 May 2021

COVID-19 guideline update from NIH, postdischarge anticoagulation, remdesivir effects

The latest news on inpatient COVID-19 care includes some changes to the NIH guidelines for COVID-19 treatment, as well as studies showing that rivaroxaban after discharge reduced clots and remdesivir helped inpatients on no or low-flow oxygen but not those who were sicker.
https://acphospitalist.acponline.org/weekly/archives/2021/12/22/1.htm
22 Dec 2021

Oxygenation by helmet, high flow didn't affect mortality in COVID-19, studies find

One trial randomized patients to helmet noninvasive ventilation or usual forms of respiratory support and found no differences. Another comparing high-flow and standard oxygen found a decrease in intubation rate with the former, but no change in any other outcome.
https://acphospitalist.acponline.org/archives/2022/09/28/free/oxygenation-by-helmet-high-flow-didnt-affect-mortality-in-covid-19.htm
28 Sep 2022

Remdesivir reduced mortality in inpatients on no or regular oxygen, meta-analysis finds

The patient-level analysis of all available trials of remdesivir still did not have the power to identify any effect of the drug on mortality in COVID-19 patients receiving high-flow oxygen or mechanical ventilation.
https://acphospitalist.acponline.org/archives/2023/03/01/free/remdesivir-reduced-mortality-in-inpatients-on-no-or-regular-oxygen-meta-analysis-finds.htm
1 Mar 2023

Critical care experts propose expanding definition of ARDS

The 2012 Berlin definition of acute respiratory distress syndrome (ARDS) should be revised to accommodate the increasing use of high-flow nasal oxygen, among other changes, an expert panel recommended.
https://acphospitalist.acponline.org/archives/2023/08/02/critical-care-experts-propose-expanding-definition-of-ards.htm
2 Aug 2023

Intermediate care unit helped surgical, COVID-19 patients

An intermediate care unit with a maximum census of six created over 1,000 available ICU bed-days over 12 months.
https://acphospitalist.acponline.org/archives/2024/02/14/free/intermediate-care-unit-helped-surgical-covid-19-patients.htm
14 Feb 2024

Biomarkers may predict which medications are effective for patients hospitalized for COVID-19

Two studies looked at biomarkers that could be used to identify high-risk hospital patients who would likely benefit from medications for COVID-19, while another recent analysis provided reassuring data on the aftereffects of acute kidney injury during COVID-19 hospitalization.
https://acphospitalist.acponline.org/archives/2024/02/28/free/biomarkers-may-predict-which-medications-are-effective-for-patients-hospitalized-for-covid-19.htm
28 Feb 2024

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