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Biomarkers may predict which medications are effective for patients hospitalized for COVID-19

Two studies looked at biomarkers that could be used to identify high-risk hospital patients who would likely benefit from medications for COVID-19, while another recent analysis provided reassuring data on the aftereffects of acute kidney injury during COVID-19 hospitalization.
https://acphospitalist.acponline.org/archives/2024/02/28/free/biomarkers-may-predict-which-medications-are-effective-for-patients-hospitalized-for-covid-19.htm
28 Feb 2024

Intermediate care unit helped surgical, COVID-19 patients

An intermediate care unit with a maximum census of six created over 1,000 available ICU bed-days over 12 months.
https://acphospitalist.acponline.org/archives/2024/02/14/free/intermediate-care-unit-helped-surgical-covid-19-patients.htm
14 Feb 2024

Critical care experts propose expanding definition of ARDS

The 2012 Berlin definition of acute respiratory distress syndrome (ARDS) should be revised to accommodate the increasing use of high-flow nasal oxygen, among other changes, an expert panel recommended.
https://acphospitalist.acponline.org/archives/2023/08/02/critical-care-experts-propose-expanding-definition-of-ards.htm
2 Aug 2023

Remdesivir reduced mortality in inpatients on no or regular oxygen, meta-analysis finds

The patient-level analysis of all available trials of remdesivir still did not have the power to identify any effect of the drug on mortality in COVID-19 patients receiving high-flow oxygen or mechanical ventilation.
https://acphospitalist.acponline.org/archives/2023/03/01/free/remdesivir-reduced-mortality-in-inpatients-on-no-or-regular-oxygen-meta-analysis-finds.htm
1 Mar 2023

Oxygenation by helmet, high flow didn't affect mortality in COVID-19, studies find

One trial randomized patients to helmet noninvasive ventilation or usual forms of respiratory support and found no differences. Another comparing high-flow and standard oxygen found a decrease in intubation rate with the former, but no change in any other outcome.
https://acphospitalist.acponline.org/archives/2022/09/28/free/oxygenation-by-helmet-high-flow-didnt-affect-mortality-in-covid-19.htm
28 Sep 2022

COVID-19 guideline update from NIH, postdischarge anticoagulation, remdesivir effects

The latest news on inpatient COVID-19 care includes some changes to the NIH guidelines for COVID-19 treatment, as well as studies showing that rivaroxaban after discharge reduced clots and remdesivir helped inpatients on no or low-flow oxygen but not those who were sicker.
https://acphospitalist.acponline.org/weekly/archives/2021/12/22/1.htm
22 Dec 2021

Late diagnoses, routine cultures, and more

Research summaries from ACP Hospitalist Weekly.
https://acphospitalist.acponline.org/archives/2021/05/recent-research.htm
15 May 2021

Support protocol for ICU patients after extubation didn't reduce reintubation rates

The trial compared a respiratory therapist-driven protocol that provided noninvasive ventilation or high-flow nasal cannula to patients after extubation to usual care and found no significant differences.
https://acphospitalist.acponline.org/weekly/archives/2021/04/14/4.htm
14 Apr 2021

Ventilation helmets didn't reduce need for respiratory support in COVID-19 patients

ICU patients with COVID-19 respiratory failure who were randomized to ventilation by helmet did have a lower rate of endotracheal intubation than those given high-flow oxygen, an Italian trial found.
https://acphospitalist.acponline.org/weekly/archives/2021/03/31/2.htm
31 Mar 2021

Blood loss anemia

A key documentation issue is whether patients have lost enough blood to become anemic.
https://acphospitalist.acponline.org/archives/2021/02/coding-corner-blood-loss-anemia.htm
15 Feb 2021

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