Search results for "Antibiotics"
Antibiotics with extended anaerobic coverage didn't improve outcomes in aspiration pneumonia
Patients with aspiration pneumonia who received extended anaerobic coverage had no reduction in mortality risk and a significantly higher risk of Clostridioides difficile than those prescribed limited anaerobic coverage.
https://acphospitalist.acponline.org/archives/2024/02/28/antibiotics-with-extended-anaerobic-coverage-didnt-improve-outcomes-in-aspiration-pneumonia.htm
28 Feb 2024
Cases from the Medical College of Wisconsin
A mycotic aneurysm, retroperitoneal hematoma, and more.
https://acphospitalist.acponline.org/archives/2024/02/28/free/cases-from-the-medical-college-of-wisconsin.htm
28 Feb 2024
New combo antibiotic shows success against complicated urinary tract infections
Microbiologic and clinical recovery occurred in 70.6% of hospitalized patients randomized to an investigational beta-lactam and beta-lactamase inhibitor combination for urinary tract infection compared to 58% of patients given meropenem, an industry-funded trial found.
https://acphospitalist.acponline.org/archives/2024/02/21/new-combo-antibiotic-shows-success-against-complicated-urinary-tract-infections.htm
21 Feb 2024
Tackling ED boarding
Hospitalists can take ownership to reduce risks for patients, especially elderly ones.
https://acphospitalist.acponline.org/archives/2024/02/21/tackling-ed-boarding.htm
21 Feb 2024
Hospital clinicians don't often use antibiograms when prescribing, survey finds
Among 193 respondents from seven U.S. health care systems, 26.9% of hospital clinicians said they used antibiograms more than once a month and 16.1% did not know that their facility had an antibiogram available.
https://acphospitalist.acponline.org/archives/2024/02/21/hospital-clinicians-dont-often-use-antibiograms-when-prescribing-survey-finds.htm
21 Feb 2024
Individualized short-course antibiotics noninferior to usual care for VAP
In a randomized open-label trial, 41% of ICU patients with ventilator-associated pneumonia (VAP) who received antibiotics for seven days or less died or had pneumonia recurrence at 60 days versus 44% of those who received usual care.
https://acphospitalist.acponline.org/archives/2024/01/31/individualized-short-course-antibiotics-noninferior-to-usual-care-for-vap.htm
31 Jan 2024
Advanced dementia and respiratory failure
A case highlights the importance of addressing prognosis before making care decisions.
https://acphospitalist.acponline.org/archives/2024/01/31/free/advanced-dementia-and-respiratory-failure.htm
31 Jan 2024
Switch to oral antibiotics noninferior for low-risk patients with S. aureus bacteremia
Complication rates were similar in patients with low-risk Staphylococcus aureus bloodstream infection who were switched to oral antibiotics versus continued on IV therapy in a European randomized trial that was stopped early due to low enrollment.
https://acphospitalist.acponline.org/archives/2024/01/24/switch-to-oral-antibiotics-noninferior-for-low-risk-patients-with-s-aureus-bacteremia.htm
24 Jan 2024
De-escalation of antibiotics effective in Enterobacterales bacteremia, Spanish trial finds
The pragmatic trial found similarly high cure rates and no difference in serious adverse events between patients who continued on an antipseudomonal beta-lactam and those de-escalated to an antibiotic without antipseudomonal activity.
https://acphospitalist.acponline.org/archives/2024/01/17/de-escalation-of-antibiotics-effective-in-enterobacterales-bacteremia-spanish-trial-finds.htm
17 Jan 2024
Risk factors may not accurately identify complicated Staphylococcus aureus bacteremia
The Infectious Diseases Society of America's criteria for determining complicated S. aureus bacteremia had low to moderate predictive value and could lead to unnecessary antibiotic treatment, according to a prospective cohort study in the Netherlands.
https://acphospitalist.acponline.org/archives/2024/01/10/risk-factors-may-not-accurately-identify-complicated-staphylococcus-aureus-bacteremia.htm
10 Jan 2024