Search results for "Anticoagulants"
Higher-dose prophylactic anticoagulation required to prevent thrombosis in hypoxemic COVID-19
Mortality and time to improvement didn't differ with twice the standard dose of heparin versus a standard or therapeutic dose, but there was a lower rate of new thromboembolic events with no increase in major bleeding, a French trial found.
https://acphospitalist.acponline.org/archives/2023/03/29/free/higher-dose-prophylactic-anticoagulation-needed-to-prevent-thrombosis-in-hypoxemic-covid-19.htm
29 Mar 2023
DOACs more effective, cost-effective than LMWH for cancer-associated thrombosis
A meta-analysis compared the direct oral anticoagulants (DOACs) apixaban, edoxaban, and rivaroxaban to low-molecular-weight heparin (LMWH) and found that apixaban was usually the most cost-effective option, but that finding hinged on the specific drug price.
https://acphospitalist.acponline.org/archives/2023/01/04/doacs-more-effective-cost-effective-than-lmwh-for-cancer-associated-thrombosis.htm
4 Jan 2023
Evidence supporting perioperative management of anticoagulants remains limited
A systematic review and meta-analysis of studies addressing perioperative management of antithrombotic therapy, developed for a clinical practice guideline by the American College of Chest Physicians, found that data were sparse overall.
https://acphospitalist.acponline.org/archives/2022/12/07/evidence-supporting-perioperative-management-of-anticoagulants-remains-limited.htm
7 Dec 2022
Studies estimate risks of bleeding, death in patients with cancer and atrial fibrillation
One recent study compared the predictive value of the HAS-BLED, ATRIA, and ORBIT scores in patients with cancer and afib, while another looked at clot, bleeding, and mortality risk with warfarin versus a direct-acting oral anticoagulant in patients with both conditions.
https://acphospitalist.acponline.org/archives/2022/12/07/studies-estimate-risks-of-bleeding-death-in-patients-with-cancer-and-atrial-fibrillation.htm
7 Dec 2022
New studies assess effects of anticoagulation during, after COVID-19
Use of intermediate, full-dose, or prophylactic anticoagulation in COVID-19 inpatients wasn't associated with any difference in in-hospital mortality in one study, while another found it was safe to discontinue anticoagulation after three months in patients with a COVID-19-associated clot.
https://acphospitalist.acponline.org/archives/2022/11/16/free/new-studies-assess-effects-of-anticoagulation-during-after-covid-19.htm
16 Nov 2022
AHA scientific statement offers guidance on LV thrombus
Treat patients with left ventricular (LV) thrombus after myocardial infarction with oral anticoagulants for three months, the American Heart Association (AHA) said, among other recommendations.
https://acphospitalist.acponline.org/archives/2022/09/21/aha-scientific-statement-offers-guidance-on-lv-thrombus.htm
21 Sep 2022
New guideline released on periop management of antithrombotic therapy
The American College of Chest Physicians issued 44 recommendations, covering use of vitamin K antagonists, heparin bridging, direct oral anticoagulants, and antiplatelet drugs in patients undergoing surgeries or procedures.
https://acphospitalist.acponline.org/archives/2022/08/17/free/new-guideline-released-on-periop-management-of-antithrombotic-therapy.htm
17 Aug 2022
Inpatient diagnosis of atrial fibrillation associated with lower use of anticoagulation
Ninety days after being diagnosed with atrial fibrillation, 51.6% of patients diagnosed in the ED were on oral anticoagulants, compared to 50.9% of those diagnosed in the hospital and 67.9% of those diagnosed as outpatients, a Canadian study found.
https://acphospitalist.acponline.org/archives/2022/08/03/inpatient-diagnosis-of-atrial-fibrillation-associated-with-lower-use-of-anticoagulation.htm
3 Aug 2022
Postop atrial fibrillation carries same stroke risk as other new-onset atrial fibrillation
Patients who first developed atrial fibrillation within 30 days of surgery were less likely to be prescribed an anticoagulant, despite similar risks of stroke and transient ischemic attack as other patients with atrial fibrillation, a study found.
https://acphospitalist.acponline.org/archives/2022/07/27/postop-atrial-fibrillation-carries-same-stroke-risk-as-other-new-onset-atrial-fibrillation.htm
27 Jul 2022
Analysis shows good adherence to stroke guidelines in stroke registry hospitals
The Get With The Guidelines study did identify some areas of potential improvement in inpatient stroke care, including more dysphagia screening and use of high-intensity statin therapy.
https://acphospitalist.acponline.org/archives/2022/07/27/analysis-shows-good-adherence-to-stroke-guidelines-in-stroke-registry-hospitals.htm
27 Jul 2022