The results contrast with previous research suggesting potential benefit from spironolactone, and the authors speculated that the drug could possibly have more effect at a higher dose or in certain subgroups of patients.
The researchers identified factors predicting which patients with gram-negative sepsis had low probability of resistance to meropenem and which had high probability of resistance to piperacillin-tazobactam, cefepime, and meropenem.
Researchers found that a single, scripted session of mindfulness training focused on acceptance of pain or hypnotic suggestion focused on changing pain sensations through imagery reduced acute pain intensity.
Patients with gastrointestinal bleeds, intracranial hemorrhages, or urgent need for surgery were given 5 g of intravenous idarucizumab to reverse the anticoagulant effect of dabigatran in the industry-funded study.
Our July issue includes a cover story looking at new drugs and data on Clostridium difficile and extensive conference coverage of Hospital Medicine 2017.