Prone positioning was helpful in patients not on mechanical ventilation, and two very small studies found positive outcomes with drugs used to treat rheumatoid arthritis. ACP members can join a bulk purchase of N95s and gowns.
An industry-funded trial that gave medical patients rivaroxaban for 45 days after hospital discharge found decreased risk for a composite end point of symptomatic venous thromboembolism, myocardial infarction, nonhemorrhagic stroke, and cardiovascular death compared to placebo.
The recommendations, based mainly on expert opinion, include general principles of empiric therapy and advice for specific pathogens, including methicillin-resistant Staphylococcus aureus and resistant gram-negative bacilli.
Researchers advised caution when using newer gadolinium-based contrast agents in patients with impaired kidney function and suggested that more research on nephrogenic systemic fibrosis (NSF) is needed in this population.