New guidance from ACP and recent trials do not support the use of hydroxychloroquine for COVID-19, and a pharmacokinetic analysis showed potential problems with lopinavir/ritonavir therapy.
Latest COVID-19 research looks at predictive biomarkers, timing of testing, health care worker infections
Lactate dehydrogenase and other biomarkers appear to predict risk of critical illness and death, and testing soon after exposure is associated with high rates of false negatives, new studies showed.
In a retrospective observational study of more than 68,000 patients in Japan, the 28-day mortality rate was 19.2% in those who received thiamine soon after hospital admission versus 17.8% in those who did not.
Compression stockings may be unnecessary for VTE prophylaxis in most patients undergoing elective surgery
In a randomized controlled trial of patients at moderate or high risk of venous thromboembolism (VTE), prophylaxis with low-molecular-weight heparin alone was noninferior to a combination of low-molecular-weight heparin and graduated compression stockings.
Although an analysis of Medicare fee-for-service data from 2014 found significant benefits to pulmonary rehab within 90 days of discharge after a hospitalization for COPD, it also revealed that only 1.5% of studied patients received this care.